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- Type Hunting, Target Shooting
- Place of origin United States
- Production history
- Designed 1877
- Manufacturer Sharps Rifle Manufacturing Company
The .45-90 Sharps cartridge is a black powder round introduced in 1877 by the Sharps Rifle Manufacturing Company. Also known as the .45 2 4/10, the cartridge developed for hunting and long-range target shooting.
The .45-90 Express is a modern adaptation of .45-90 Sharps, which uses the same 2.4-inch case but uses smokeless powder loaded to pressures up to 45,000 psi. With a 26-inch barrel, the .45-90 Express is capable of over 4,200 ft-lbs (5694 J) muzzle energy.